What is the recommended approach to antibiotic selection for a suspected urinary tract infection in a 2-year-old with no penicillin allergy?

• A. Choose an agent with good urinary penetration (e.g., amoxicillin-clavulanate or a cephalosporin) and tailor to local guidelines.
• B. Use an antibiotic with poor urinary penetration
• C. Use penicillin alone
• D. Use a macrolide with poor urinary penetration

Answer: (B)